Erectile Dysfunction

Impotence is a highly treatable condition yet many of those suffering from it are reluctant to seek treatment. Since the launch of Viagra, Cialis and Levitra, oral medicines have radically improved the treatment of ED. These drugs work for the majority of men affected, whatever the cause. Choosing which ED medication is best is a matter of trial an error, although there are particular characteristics of each treatment which may help you decide which may suited to your own personal needs. Erectile Dysfunction treatment comparison.

PharmaDoctor can provide you with an online prescription for oral erectile dysfunction medication following an online consultation with our GMC and EU-registered doctors.

What is it?

Viagra is a diamond-shaped blue pill containing the active ingredient sildenafil. Launched by Pfizer in 1998, it was the first oral treatment of its kind for erectile dysfunction. On average, it is effective for 78 per cent of men.

How does it work?

Erections are primarily achieved through blood flow. Viagra works by blocking an enzyme called phosphodiesterase (PDE5), which in turn means that the blood vessels in the penis remain relaxed for a longer period allowing for increased blood flow. It also has the effect of 'trapping' the blood in the penis helping to produce longer-lasting erections. Viagra is not an aphrodisiac and only allows an erection to result following sexual stimulation.

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Main points to consider

  • First time customers should try the standard dose of 50mg first. Only if this proves ineffective, should you try the stronger dose of 100mg.
  • Viagra should be taken one hour prior to sexual activity. It remains effective for approximately four hours and should not be taken more than once in any 24-hour period.
  • Before taking it you should avoid eating fatty food and alcohol as both will affect the absorption of the drug into your system.
  • Side effects may include Congestion, Diarrhea, Flushing, Headaches, Bluish Vision
  • It cannot be mixed with any Nitrate-Based Medicine

For further Information please read the Patient Information Leaflet carefully

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What is it?

Cialis is an almond-shaped yellow pill containing the active ingredient tadalafil. Due to the fact that its can remain active for up to 36 hours, it has been nicknamed 'the weekender'. On average, it is effective for 80 per cent of men and is proving to be a popular choice for first time customers.

How does it work?

Cialis works in the same way as Viagra and Levitra by improving blood flow in the penis through blocking an enzyme called phosphodiesterase (PDE5). It also keeps the blood in the penis for longer which produces longer-lasting erections. Cialis will not leave you with a permanent erection (this occurs in rare cases, with a condition known as priapism which must be treated medically)

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Main points to consider

  • Cialis should be taken between 30 minutes and one hour prior to sexual activity. It should not be taken more than once in any 48 hour period. Patients should start with the standard dose of 10mg. Only if this proves ineffective, should you try the stronger dose of 20mg.
  • With a 36 hour 'window of opportunity' - Cialis lasts the longest of all the oral ED treatments. However, because the dose is low and gradual, Cialis may be too weak for some individuals.
  • The absorption of Cialis is unaffected by food or alcohol (in moderation).
  • Its side effects are generally mild and short-lived but can include indigestion, congestion, facial flushing, headaches and dizziness.
  • It cannot be mixed with any Nitrate-Based Medicine

For further Information please read the Patient Information Leaflet carefully

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What is it?

Generic tadalafil is an erectile dysunction treatment and it takes its name from the active ingredient, tadalafil, the same as in Cialis. As the patent on Cialis, currently held by Eli Lilly, expires later this year, generic tadalafil will become available from a number of different providers. As it will be produced by different licensed manufacturers, the shape, colour and taste of the tablets is likely to vary. However, the chemical make-up of the treatment will be the same as Cialis, in the same doses, so it will work in the same way. We also expect the new legal generics to cost less than the original brand Cialis.

How does it work?

Generic tadalafil will work in the same way as original brand Cialis, Viagra and Levitra, by improving blood flow in the penis through blocking an enzyme called phosphodiesterase (PDE5). Like Cialis, the effects of the treatment will be longer lasting, in comparison with other ED medication. Cialis will not, however, leave you with a permanent erection (this occurs in rare cases, with a condition known as priapism which must be treated medically)

Main points to consider

  • Generic tadalafil should be taken between 30 minutes and one hour prior to sexual activity. It should not be taken more than once in any 48 hour period. Patients should start with the standard dose of 10mg. Only if this proves ineffective, should you try the stronger dose of 20mg.
  • The expiration of the patent on Cialis is only on the 10mg and 20mg doses. Cialis Once a Day, in the 2.5mg and 5mg doses, will remain under patent.

What is it?

Released by Bayer in 2003, Levitra is a round orange pill containing the active ingredient vardenafil, which is an effective treatment for male erectile dysfunction. Levitra has been shown to have milder side effects compared to the other treatments.

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How does it work?

Levitra works on the same principle as Viagra and Cialis by improving blood flow to the penis and trapping it there. It does this by inhibiting an enzyme called phosphodiesterase (PDE5).This leads to erections which are sufficient for sexual intercourse to take place.

Main points to consider

  • Patients should start with the standard dose of 10mg. Only if this proves ineffective, should you try the stronger dose of 20mg.
  • Levitra should taken (with or without food) between 30 minutes and one hour prior to sexual activity. It should not be taken more than once in any 24-hour period.
  • The drug remains effective for between 5 and 9 hours
  • It cannot be mixed with any Nitrate-Based Medicine
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For further Information please read the Patient Information Leaflet carefully

What is it?

Levitra Orodispersible is the first new version of Levitra that has been released by Bayer. Its an oral dispersible version of their product and may have been developed in response to the very popular generic soft tab versions available from Indian or Chinese websites.

Other than being a soluble soft tablet version it is identical in every other way to the regular Levitra pills that have been available since 2003. However as it is ingested differently it does have less side effects than the regular treatments.

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How is it different to regular Levitra?

Just like the standard Levitra pill Levitra Orodispersible is meant to be taken as and when needed. However unlike Levitra this new soluble version is meant to be simply placed on or under the tongue and left to dissolve before it is then swallowed. This version of Levitra is a fast acting impotence treatment which has a reaction time of as low as 10 minutes. Further advantages of the soluble version is that it bypasses the gastro intestinal tract meaning it’s not digested causing no indigestion or dyspepsia as well as being helpful for those that find it hard or can't to swallow.

So as well as having reduced side effects and faster reaction times its new packaging is sleeker discreet and more suited to its image as a life style drug even with a fresh minty aftertaste.

Other than these differences the treatment is identical to the other Levitra pills as it has the same active ingredients.

Main points to consider

  • There is only one dose available 10mg. If the dose is not strong enough its recommended to use levitra 20mg pills
  • Do not take more than one soluble soft tab a day. Allow 24 hours before a repeat dose.
  • As it has a faster reaction time it can be taken just before intercourse
  • Just like the other impotence treatments Levitra Orodispersible should not be taken with any Nitrate-Based Medicine
  • Posh packaging may come in handy in some situations.

For further Information please read the Patient Information Leaflet carefully

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What is it?

Cialis One-A-Day is the latest oral impotence treatment. It contains the phosphodiesterase type 5 inhibitor (PDE5) called Taladafil as its active ingredient. It comes in two doses - 2.5mg and 5mg and, as the name suggests, is designed to be taken once daily.

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How is it different to regular Cialis?

It is identical in structure to the well known Cialis and contains the same phosphodiesterase type 5 inhibitor (PDE5), taladafil. However, its new lower dosing format means that unlike existing oral treatments for erectile dysfunction, including Cialis, Viagra and Levitra, Cialis One-A-Day can be taken as part of a daily routine.

Main points to consider

  • First time users should try the lower dose of 2.5mg first. Only if this proves ineffective, should you try the stronger dose of 5mg.
  • Take 1 tablet at about the same time every day, with or without food
  • Cialis One-A-Day is a very effective option for men who anticipate more frequent sexual activity and who have a good track record with the other oral impotence treatments.
  • It takes about 4-5 days to begin working properly and that it only works in response to sexual stimulation.
  • It cannot be mixed with any Nitrate-Based Medicine

For further Information please read the Patient Information Leaflet carefully

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Find out which treatment is best for you

Want to know which treatment is best for you? find out by trying all the treatments with our ED trial pack.

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About Erectile Dysfunction

Impotence is when a man is unable to achieve or maintain an erection long enough or firm enough for satisfactory sexual activity. The medical term for this is erectile dysfunction.

An inability to achieve an erection every now and then is common in adult men (especially due to alcohol or exhaustion). In some cases, it is a temporary condition that will go away. In other cases, it can be an ongoing problem that can have damaging consequences for a man’s relationship and self esteem. If you have difficulty having or keeping an erection more than 25% of the time, it is considered a problem and therefore requires treatment.

Erection problems can be a red flag that something is not right with the body's system. If you believe you are suffering from ED, a visit to the doctor is important before seeking treatment online. This is to rule out the possibility of more serious underlying physical conditions such as diabetes.

The common causes of impotence can be divided into physical and psychological. It is believed that 70 per cent of cases have physical causes and 30 per cent psychological causes. However, an erection requires the interaction of your brain, nerves, hormones, and blood vessels so often it can be a combination of the two.

Physical Causes

  • Diseases and conditions such as diabetes, high blood pressure, heart or thyroid conditions, poor blood flow, depression, or neurologic disorders (such as multiple sclerosis or Parkinson's disease)
  • Medications such as blood pressure medications (especially beta-blockers), heart medications (such as digoxin), some peptic ulcer medications, sleeping pills, and antidepressants
  • Nerve damage from prostate surgery
  • Spinal cord injury
  • Smoking, alcohol, or recreational drug use

Psychological Causes:

A man who has normal erectile responses during masturbation, or who regularly awakens with an erection, is likely to have a psychological basis for impotence. These include:

  • Stress, fear, exhaustion, anxiety, or anger
  • Relationship Problems
  • Performance Anxiety
  • Low Self Esteem